

Step 1:
Shout for Help/Activate Emergency Response
Start CPR
• Give oxygen
• Attach monitor/defibrillator
Rhythm shockable?
Yes
No
Step 2:
VF/VT
Step 3:
Shock
Step 4:
CPR 2 min
• IV/IO access
Rhythm shockable?
Step 5:
Shock
Step 6:
CPR 2 min
• Epinephrine every 3-5 min
• Consider advanced airway, capnography
Rhythm shockable?
Step 7:
Shock
Step 8:
CPR 2 min
• Amiodarone
• Treat reversible causes
Step 9:
Asystole/PEA
Step 10:
CPR 2 min
• IV/IO access
• Epinephrine every 3-5 min
•Consider advanced airway, capnography
Rhythm shockable?
Step 11:
CPR 2 min
• Treat reversible causes
Rhythm shockable?
Step 12:
• If no signs of return of spontaneous circulation (ROSC), go to 10 or 11
• If ROSC, go to Post-Cardiac Arrest Care
Go to 5 or 7
CPR Quality
• Push hard (≥2 inches [5 cm]) and fast (≥100/min) and allow complete chest recoil
• Minimize interruptions in compressions
• Avoid excessive ventilation
• Rotate compressor every 2 minutes
• If no advanced airway, 30:2 compression-ventilation ratio
• Quantitative waveform capnography
o If PETCO2 <10mm Hg, attempt to improve CPR quality
• Intra-arterial pressure
o If relaxation phase (diastolic) pressure <20 mm Hg, attempt to improve CPR quality
Return of Spontaneous Circulation (ROSC)
• Pulse and blood pressure
• Abrupt sustained increase in PETCO2 (typically ≥40 mm Hg)
• Spontaneous arterial pressure waves with intra-arterial monitoring
Shock Energy
• Biphasic: Manufacturer recommendation (eg, initial dose of 120-200 J); if unknown, use maximum available. Second and subsequent doses should be equivalent, and higher doses may be considered.
• Monophasic: 360 J
Drug Therapy
• Epinephrine IV/IO Dose:
1 mg every 3-5 minutes
• Vasopressin IV/IO Dose:
40 units can replace first or second dose of epinephrine
• Amiodarone IV/IO Dose:
First dose: 300 mg bolus.
Second dose: 150 mg.
Advanced Airway
• Supraglottic advanced airway or endotracheal intubation
• Waveform capnography to confirm and monitor ET tube placement
• 8-10 breaths per minute with continuous chest compressions
Reversible causes
• Hypovolemia
• Hypoxia
• Hydrogen ion (acidosis)
• Hypo-/hyperkalemia
• Hypothermia
• Tension pneumothorax
• Tamponade, cardiac
• Toxins
• Thrombosis, pulmonary
• Thrombosis, coronary
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