

First, shout for Help/Activate Emergency Response
Then Start CPR
• Give oxygen
• Attach monitor/defibrillator
Then start cycle 1, with 2 minutes per cycle
Check RhythmIf VF/VT Shock
Continuous CPR
Monitor CPR quality
Continuous CPR
After 2 minutes Check Rhythm again
If Return of Spontaneous Circulation occurs (ROSC)
Proceed to Post-Cardiac Arrest Care
Otherwise, if VF/VT Shock and repeat cycle
Meanwhile consider the following:
Drug Therapy
IV/IO access
Epinephrine every 3-5 minutes
Amiodarone for refractory VF/VT
Consider Advanced Airway
Quantitative waveform capnography
Treat Reversible Causes
Additional Info
CPR Quality
• Push hard (≥2 inches [5 cm]) and fast (≥100/min) and allow complete chest recoil
• Minimize interruptions in compressions
• Avoid excessive ventilation
• Rotate compressor every 2 minutes
• If no advanced airway, 30:2 compression-ventilation ratio
• Quantitative waveform capnography
o If PETCO2 <10mm Hg, attempt to improve CPR quality
• Intra-arterial pressure
o If relaxation phase (diastolic) pressure <20 mm Hg, attempt to improve CPR quality
Return of Spontaneous Circulation (ROSC)
• Pulse and blood pressure
• Abrupt sustained increase in PETCO2 (typically ≥40 mm Hg)
• Spontaneous arterial pressure waves with intra-arterial monitoring
Shock Energy
• Biphasic: Manufacturer recommendation (120-200 J); if unknown, use maximum available. Second and subsequent doses should be equivalent, and higher doses may be considered.
• Monophasic: 360 J
Drug Therapy
• Epinephrine IV/IO Dose: 1 mg every 3-5 minutes
• Vasopressin IV/IO Dose: 40 units can replace first or second dose of epinephrine
• Amiodarone IV/IO Dose: First dose: 300 mg bolus. Second dose: 150 mg.
Advanced Airway
• Supraglottic advanced airway or endotracheal intubation
• Waveform capnography to confirm and monitor ET tube placement
• 8-10 breaths per minute with continuous chest compressions
Reversible causes
• Hypovolemia
• Hypoxia
• Hydrogen ion (acidosis)
• Hypo-/hyperkalemia
• Hypothermia
• Tension pneumothorax
• Tamponade, cardiac
• Toxins
• Thrombosis, pulmonary
• Thrombosis, coronary
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